Don't say yes just because someone else wants you to. Opportunities abound for you so it can't hurt to research alternatives. Taking a different path may get you to your destination sooner. If it doesn't work for you today, perhaps you shouldn't be doing it at all.
Careerwise, it's possible that you'll find a new impetus. Take stock of your health: don't any longer have recourse so frequently to chemical drugs and don't treat certain ills with contempt. You'll have reasons for dissatisfaction with your home life; try to relativize things. Your love affairs will be tense, probably because you expect too much from them.